Anti-Nutrient

Molecule:

Trypsin inhibitor

Foods:

Grains and legumes.
Trypsin inhibitor

How to Neutralize:

Partially by cooking, sprouting.

Negative Effects:

Growth inhibition and pancreatitis.

Protease inhibitors: Protease inhibitors are widely distributed within the plant kingdom, including the seeds of most cultivated legumes. Protease inhibitors have the ability to inhibit the activity of proteolytic enzymes within the gastrointestinal tract of animals (Liener and Kakade, 1980). Trypsin inhibitor and chymotrypsin inhibitor are protease inhibitors occurring in raw legume seeds. Protease inhibitors are the most commonly encountered class of antinutritional factors of plant origin. These inhibitors have been reported to be partly responsible for the growth-retarding property of raw legumes. The retardation has been attributed to inhibition of protein digestion but there is evidence that pancreatic hyper- activity, resulting in increased production of trypsin and chymotrypsin with consequent loss of cystine and methionine is also involved (McDonald et al., 1995). Trypsin inhibitors have been implicated in reducing protein digestibility and in pancreatic hypertrophy (Liener, 1976). Trypsin inhibitors are polypeptides that form well characterized stable complexes with trypsin on a one-to-one molar ratio, obstructing the enzymatic action (Carlini and Udedibie, 1997). Protease inhibitors are inactivated by heat especially moist heat, because of even distribution of heat (Bressani and Sosa, 1990; Liener, 1995).

Food Name
Food Group
Protein (g)
Fat (g)
Carbohydrates (g)
Calories
Starch (g)
SucroseG
Glucose (g)
Fructose (g)
Lactose (g)
Maltose (g)
Alcohol (g)
Water (g)
Caffeine (mg)
Theobromine (mg)
Sugar (g)
Fiber (g)
Calcium (mg)
Iron (mg)
Magnesium (mg)
Phosphorus (mg)
Potassium (mg)
Sodium (mg)
Zinc (mg)
Copper (mg)
Flouride (mcg)
Manganese (mg)
Selenium(mcg)
Vitamin A(IU)
Retinol (mcg)
Beta Carotene (mcg)
Alpha Carotene (mcg)
Vitamin E (mg)
Vitamin D (mcg)
Lutein and Zeaxanthin
Vitamin C (mg)
Thiamin (B1) (mg)
Riboflavin (B2)(mg)
Niacin(B3)(mg)
Vitamin B5(mg)
Vitamin B6 (mg)
Folate (B9) (mg)
Choline (mg)
Cholesterol (mg)
Saturated Fat (g)
Net Carbs
Rye grain
Cereal Grains and Pasta
10.34
1.63
75.86
338
NULL
0.71
0.16
0.11
0
0
0
10.6
0
0
0.98
15.1
24
2.63
110
332
510
2
2.65
0.367
NULL
2.577
13.9
11
0
7
0
0.85
0
210
0
0.316
0.251
4.27
1.456
0.294
38
30.4
0
0.197
60.76
Sorghum grain
Cereal Grains and Pasta
10.62
3.46
72.09
329
NULL
NULL
NULL
NULL
NULL
NULL
NULL
12.4
NULL
NULL
2.53
6.7
13
3.36
165
289
363
2
1.67
0.284
NULL
1.605
12.2
0
0
NULL
NULL
0.5
0
NULL
0
0.332
0.096
3.688
0.367
0.443
20
NULL
0
0.61
65.39
Triticale flour, whole-grain
Cereal Grains and Pasta
13.18
1.81
73.14
338
NULL
NULL
NULL
NULL
NULL
NULL
0
10.01
NULL
NULL
NULL
14.6
35
2.59
153
321
466
2
2.66
0.559
NULL
4.185
NULL
0
0
NULL
NULL
0.9
0
NULL
0
0.378
0.132
2.86
2.167
0.403
74
NULL
0
0.318
58.54
Wheat flour, whole-grain
Cereal Grains and Pasta
13.21
2.5
71.97
340
57.77
0.36
0
0.05
NULL
NULL
0
10.74
0
0
0.41
10.7
34
3.6
137
357
363
2
2.6
0.41
NULL
4.067
61.8
9
0
5
0
0.71
0
220
0
0.502
0.165
4.957
0.603
0.407
44
31.2
0
0.43
61.27
Beans, pinto, mature seeds, canned, solids and liquids, low sodium
Legumes and Legume Products
4.6
0.56
15.18
82
NULL
NULL
NULL
NULL
NULL
NULL
0
78.19
0
0
1.02
4.6
47
1.47
33
92
276
146
0.56
0.162
NULL
0.318
3.7
0
0
0
0
0.55
0
0
0.7
0.052
0.016
0.268
0.136
0.135
24
20.8
0
0.116
10.58
Beans, yellow, mature seeds, cooked, boiled, with salt
Legumes and Legume Products
9.16
1.08
25.28
144
NULL
NULL
NULL
NULL
NULL
NULL
0
62.98
0
0
0.34
10.4
62
2.48
74
183
325
241
1.06
0.186
NULL
0.455
1.3
2
0
0
0
0.94
0
0
1.8
0.187
0.103
0.708
0.229
0.129
81
35.2
0
0.279
14.88
Beans, white, mature seeds, cooked, boiled, with salt
Legumes and Legume Products
9.73
0.35
25.09
139
NULL
NULL
NULL
NULL
NULL
NULL
NULL
63.08
NULL
NULL
0.34
6.3
90
3.7
63
113
561
242
1.38
0.287
NULL
0.636
1.3
0
0
0
0
0.94
0
0
0
0.118
0.046
0.14
0.229
0.093
81
35.1
0
0.091
18.79
Broadbeans (fava beans), mature seeds, cooked, boiled, with salt
Legumes and Legume Products
7.6
0.4
19.65
110
NULL
NULL
NULL
NULL
NULL
NULL
NULL
71.54
NULL
NULL
1.82
5.4
36
1.5
43
125
268
241
1.01
0.259
NULL
0.421
2.6
15
0
9
0
0.02
0
0
0.3
0.097
0.089
0.711
0.157
0.072
104
30.6
0
0.066
14.25
Chickpeas (garbanzo beans, bengal gram), mature seeds, cooked, boiled, with salt
Legumes and Legume Products
8.86
2.59
27.42
164
NULL
NULL
NULL
NULL
NULL
NULL
NULL
60.21
NULL
NULL
4.8
7.6
49
2.89
48
168
291
243
1.53
0.352
NULL
1.03
3.7
27
0
16
0
0.35
0
0
1.3
0.116
0.063
0.526
0.286
0.139
172
42.8
0
0.269
19.82