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Dr Louis Newburgh, who thinks obesity is caused by overeating, publishes a case study on a man doing a 4,177 calorie all meat diet for 7 months but admits that there are no problems when not overdoing the protein content.

January 1, 1930

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The Nephropathic Effect in Man of a Diet High in Beef Muscle and Liver.

Protein Malnutrition
Facultative Carnivore
Fat
Protein
Carnivore Diet

The Nephropathic Effect in Man of a Diet High in Beef Muscle and Liver.

Author(s) : Newburgh, L. H.Falcon-lesses, M.Johnston, Margaret W.

Author Affiliation : Med. School, Univ. of Michigan, Ann Arbor.

Journal article : American Journal of Medical Sciences 1930 Vol.179 pp.305-10 ref.8

Abstract : The authors have previously shown that rats living on a diet rich in animal tissues (muscle and liver) gradually developed sclerosis of the kidney. In the present investigation a normal man, aged 32, was given a diet containing less than 100 gm. protein daily, for a preliminary period of 35 days. There was no albumen in the urine during this period and the number of urinary casts averaged 50 per hour (ADDIS gives the average figure in group of students as 87). During the next 6 months the man ate a diet containing 327 gm. of animal protein and with a total calorie value of 4, 177. Beef liver, veal round, beef tenderloin and dried beef were given, about one-quarter of the protein being liver. Only 31 per cent. of the calories of the diet represented animal protein. No clinical or subjective abnormalities appeared. There was a gradual increase in the urine albumen which reached 2 to 4 mgm. of protein per hour in the 6th month. The cast counts during the first 7 weeks were within the normal range. Afterwards the counts were definitely pathological and during the last 6 weeks the average count was 1, 283 (15 X normal average). At first the casts were hyaline; gradually more and more granular casts appeared, and during the last 6 weeks, some were cellular and the hyaline type were in the minority. After returning to a diet of his own choice, in which meat was avoided, the man's urine became normal in 10 days. A diet containing the same proportions of animal protein was found not to affect the kidney of the rat. There are a number of observations which appear to show that an exclusive meat diet is not harmful to the kidneys of man. The Eskimos are cited in this regard, but a recent survey of a number of middle-aged Eskimos shows a definitely higher degree of albuminuria than in the policy holders of a large American insurance company. Furthermore the Eskimos have presumably over many generations become adapted to their diet. The recent investigation on 2 arctic explorers (this Bulletin, 1929, v. 4, 829), showed no renal impairment with " an exclusive meat diet " for 12 months. This diet only contained 100-140 gm. protein daily and 80 per cent. of the energy was in the form of fat.
H. N. H. Green.